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TESE is a testicular biopsy, which is performed before an IVF cycle to look for live sperm in men who do not have sperm in the ejaculate (azoospermic men). Azoospermia affects 1% of the male population. The live spermatozoids found in the testicle are either used at that moment of extraction to fertilize eggs or are frozen and used later in an IVF/ICSI cycle.